GLH Smart Cart

We are thrilled to announce the commercial launch of the GLH Smart-Cart, an AI-powered, self-navigating quality control platform designed to revolutionize laboratory automation. Developed in collaboration with MSI and Telamon Robotics, this cutting-edge product enhances the efficiency and precision of automated liquid handling systems.

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GLH Smart Cart

Automated Liquid Handler QC Excellence

The GLH QC Smart Cart is a semi-to-fully automated machine that can move from station-to-station and provide application support of liquid handler processes and quality control.

  • Streamline the process of Quality Control
  • Improve testing performance
  • Maximize operational readiness
  • Automated and optimize scheduled testing cycles during times of incubation or down times or in parallel with other processes
  • Enable integration with islands of automation
  • ALH and Volume Verification Instrument agnostic

Volume from 1 nL to 10 mL

Supports up to 1536-channels

Aqueous or DMSO

Wide range of well-shape support

Flat bottom
U-bottom
V-bottom

Compliance

ISO 23783-2:2022
ISO IWA 15:2015
21 CFR Part 11
NIST Traceable (optional)

Workflow

Prep Plate

Dispense the reference plate and test plate with GLH QC Reagents and mix with plate shaker.

Read Plate

Simply scan the reference plate and the test plate, whether using our GLH QC Absorbance Mini Reader or your own plate reader.

Analyze and Report

GLHTracker software streamlines the entire workflow providing quality-compliant pass/fail results and detailed data for troubleshooting and optimization.

Addressing Industry Challenges

Historically, quality control systems relied on manual testing by technicians, which introduced human error and required specialized knowledge. While robotic arms have replaced manual pipetting in many applications, they have not adequately addressed testing liquid handlers. The GLH QC Smart-Cart bridges this gap by offering:

  • Versatile Volume Verification: Supports single-dye, dual-dye, fluorescence, and gravimetric methods, tailored for multi-channel testing, environmental variability, and scalability.
  • AI-Driven Optimization: Uses artificial intelligence (AI) and machine learning (ML) algorithms to evaluate performance and recommend adjustments, ensuring consistent and reliable results.*
  • On-Deck and Off-Deck Testing: Features a flexible design for volumetric verification and calibration directly on or off the deck of automated liquid handlers (ALHs).

Innovative Features and Functionality

The GLH QC Smart-Cart integrates seamlessly with diverse laboratory environments. Key features include:

  • Modular Design: Compatible with a wide range of liquid handler robot decks, robotic arms, grippers, readers, and microplate scales.
  • Open Communication Standards: Utilizes SILA for interoperability among laboratory instruments, with support for additional programming protocols.
  • Performance Testing Library: A comprehensive database of testing methods to control and optimize various liquid handlers and absorbance readers.
  • Predictive Maintenance: Learning algorithms assess and recommend maintenance schedules, minimizing downtime and maximizing operational efficiency.*
Typical Test Time < 10 minutes + read time (With established liquid class; robot and reader methods)
Tip/Channel Configurations 24-Well; 96-Well; 384-Well; 1536-Well
Compatible Plate Formats 24-Well; 96-Well; 384-Well; 1536-Well
Dye Solutions Tartrazine-Based
Operating Volume Range 24-Well Format: 0.05 – 10,000 μL
96-Well Format: 0.01 – 2,000 μL
384-Well Format: 0.003 – 500 μL
1536-Well Format: 0.001 – 80 μL
Traceable Volume Range* 24-Well Format: 0.05 – 5,000 μL
96-Well Format: 0.01 – 1,000 μL
384-Well Format: 0.003 – 250 μL
1536-Well Format: 0.001 – 40 μL
Uncertainty (Inaccuracy)** + 2.0% : Nano, Micro, Bulk, Large
+ 4.0% : X-Large
Random Error (Imprecision)** + 1.0% :Nano, Micro, Bulk, Large
+ 2.0% : X-Large
General Operating Conditions Temperature: 13 – 30 C
Relative Humidity: 20 – 70%
Traceable Operating Conditions*** Temperature: 17 – 27 C
Relative Humidity: 30 – 60%
Notes *Volume Measurement outside the indicated ranges are not traceable to national and international standards and declarations of uncertainty and random error are not made.
**Stated Specifications apply when the Byonoy Absorbance 96 Reader, GLH Verification Plates, and the GLH Validation Reference Plate (using the “Auto-Generate” function) is used with Aqueous and DMSO-Based Test Solutions.
***Tests performed outside the indicated operating conditions are not traceable to national or international standards and system declarations of uncertainty and random error are not made.
Warranty The GLH QC Kit is for laboratory research use by trained users. Determination of their suitability for specific end-use is the responsibility of the user, who assumes all liability for loss or damage arising out of the use of the product. Warranty is limited to replacement of defective materials, if returned with authorization, within 1-year of purchase date.
Volume, Instrument, Reader, and Pipette Tip Testing with GLH QC Kit – Webinar – April 19, 2023

SLAS 2023 Poster: Turnkey Qualification of Liquid Handlers and Manual Pipettes

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