Poster Presentation(s)

Laboratory Management or Informatics Session(s)

Poster Title: Study Conducted of Essential ISO Standards for Liquid Handling and Pipetting

Automated Liquid Handling (ALH) equipment is an essential component of laboratories. Used to boost the productivity, repeatability of volume transfers, ALH must be optimized to achieve precision and accuracy in liquid delivery. To address this need, AT (Automation Trainer LLC), is a leading expert in laboratory automation and training, and a supplier of liquid handling quality assurance measurement systems for calibrating equipment. Based on years of practical laboratory experience teaching thousands of students, we have developed a comprehensive curriculum for ALH instruction captured in a single dye calibration kit meeting industry demand and user pains. Users need optimum performance out of their equipment to not experience process cost impacts and validate processes for QA/QC. A single dye calibration kit is needed to assure users of proper functionality after every service call, install, move, and operation to qualify demonstrations and operational requirements. Market opportunity– Is to satisfy the user driven market need of a single dye non-NIST traceable calibration kit from educationally developed good practices adopted from trustworthy relationships with users and vendors and long withstanding hands on trainings based on years of industry experience dedicated to our students. We have developed a user community through our educational course and can satisfy their pain of having an easy, trust worthy, reliable, time efficient, and cost effective method for calibrating their equipment for their specific instrument, liquid class, and volume range.

  • PETAR STOJADINOVIC, Will Herms, Kane Fong, Automation TrainerLLC
  • Dr. Martin Neuenschwander, Institute of Molecular Pharmacology FMP
  • Robert Larkin Calibrex-DX

Poster Title: Study conducted of essential ISO Standards for Liquid Handling and Pipetting

Laboratory Management or Informatics Session(s)

Poster Title: Study conducted of essential ISO Standards for Liquid Handling and Pipetting

Automated liquid handing (ALH) is an essential component of life science and chemical laboratories, however, the methods and practices for performing volume verifications have yet to be fully standardized and implemented. The International Organization for Standardization (ISO) has published generalized metrological standards for liquid handling, but the responsibility of applying these guidelines to the calibration of ALHs ultimately rests on individual labs and service companies that may lack the specific knowledge required. The lack of standard volume verification practices is particularly acute in high throughput labs and when extremely low volumes (less than 1 microliter) are used. Our Presentation addresses the fundamental metrological requirements of ISO certification and the application of these standards to ALH devices. We discuss physical requirements and how to create and maintain NIST traceability, as well as the training and certification requirements needed to ensure consistent application of metrological standards. Challenges unique to ALHs such as method development and optimization, software standardization, and high throughput volume verification will be addressed. The future development of ISO standards specifically targeting high throughput, low volume ALHs will be discussed in detail in the context of similar proposals such as IWA 15. We will also host a conferee networking event to stimulate discussion.

  • Petar Stojadinovic, Automation Trainer LLC
  • William Herms, Senior Biologist Automation Trainer LLC
  • Dr. John Coller, Functional Genomics Group, Stanford University
  • Robert Larking, Calibrex DX Inc
Quality QA/QC
Lab Automation, Quality Control, Instrumentation, Process Monitoring
Process Analytical Techniques
Application